PRP
Platelet-Rich Plasma - a treatment that uses concentrated platelets from your own blood, injected into a joint to potentially promote healing and reduce inflammation.
Extended Definition
Platelet-Rich Plasma (PRP) therapy is a regenerative medicine treatment that harnesses the healing properties of your own blood. Platelets are small blood cells best known for their role in blood clotting, but they also contain growth factors and proteins that can stimulate tissue repair and reduce inflammation.
To create PRP, a healthcare provider draws a small amount of your blood (similar to a routine blood test) and processes it in a centrifuge, which spins the blood to separate and concentrate the platelets. The resulting platelet-rich plasma contains 3-10 times more platelets than normal blood. This concentrated PRP is then injected into the affected joint, where the growth factors may help reduce inflammation, stimulate cartilage and other tissue regeneration, and improve pain and function.
PRP has gained attention as a potential treatment for knee osteoarthritis and other joint conditions. While some studies and patient reports suggest benefits—including pain reduction and improved function that may last 6-12 months—the evidence is still evolving. Results can vary significantly between patients, and the treatment is not yet standardized (different preparation methods and platelet concentrations are used). Importantly, PRP is not typically covered by Medicare or most insurance plans, making it an out-of-pocket expense that can range from $500 to $2,000 per treatment. More research is needed to determine who is most likely to benefit from PRP, the optimal preparation methods, and how it compares to other treatment options like hyaluronic acid injections.
Related Terms
More Treatments Terms
View allCorticosteroid
A powerful anti-inflammatory medication similar to cortisol (a hormone naturally produced by the body) that can be injected into joints to quickly reduce swelling and pain.
Hyaluronic Acid
A naturally occurring substance found in synovial fluid that gives it its thick, gel-like consistency and lubricating properties. Also used as an injection treatment for joint pain.
Molecular Weight
The size of a molecule measured in daltons. In hyaluronic acid products, molecular weight affects how thick and long-lasting the injection is, with higher molecular weight typically providing longer relief.
NSAID
Non-Steroidal Anti-Inflammatory Drug - a type of medication that reduces pain, inflammation, and fever by blocking enzymes that produce inflammatory chemicals in the body.
Nerve Block
An injection of anesthetic near specific nerves to temporarily block pain signals. Used for diagnosis, pain relief, or before surgery. Effects last hours to months depending on medication used.