Same Volume, Different Sources
Gel-One and Durolane both deliver 3 mL of HA in a single injection—but they come from completely different sources. This matters if you have bird allergies.
Side-by-Side Comparison
| Factor | Gel-One | Durolane |
|---|---|---|
| Source | Avian (rooster comb) | Non-animal (NASHA) |
| Bird allergy safe | No | Yes |
| Volume | 3 mL | 3 mL |
| Self-pay | $700-$1,000 | $900-$1,300 |
| Duration | 4-6 months | 6+ months |
| Manufacturer | Zimmer Biomet | Bioventus |
Key Differences
Gel-One Advantages
- Lower cost - Typically $200-300 less
- Orthopedic expertise - From a joint replacement leader
- Wide availability
Durolane Advantages
- Bird allergy safe - No animal products
- Potentially longer relief - Reported 6+ months
- Unique positioning - Only non-avian single-shot
Making Your Decision
Choose Gel-One if:
- No bird/egg allergies
- Cost is a priority
- Your provider stocks it
Choose Durolane if:
- You have avian allergies
- Prefer non-animal products
- Duration is a priority
The Bottom Line
Both are effective single-injection options with identical volumes. Allergies determine the choice—Durolane for bird-sensitive patients, Gel-One for cost-conscious patients without allergies.
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