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Cortisone Injection FAQs: Steroid Shots for Joint Pain Questions

Get answers to common questions about cortisone injections for joint pain. Learn about how often you can get steroid shots, side effects, how long they last, and how they compare to gel injections.

20 questions answered Medically Reviewed by Medical Review Team, MD

Cortisone injections are one of the most common treatments for joint pain and inflammation. This FAQ covers everything you need to know about steroid shots, including how often you can receive them, potential side effects, and how they compare to other treatment options.

Have more questions? Explore our treatment guides or find a joint pain specialist near you.

A cortisone injection, also called a steroid shot or corticosteroid injection, delivers powerful anti-inflammatory medication directly into a painful joint. It reduces inflammation and swelling, providing rapid pain relief for arthritis, bursitis, and other joint conditions.

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Cortisone is a synthetic version of cortisol, your body's natural anti-inflammatory hormone. When injected into a joint, it quickly reduces inflammation, decreases swelling, and calms irritated nerves. This provides significant pain relief, often within days.

Relief typically lasts 4-8 weeks, though some patients experience benefits for several months. Duration varies based on the severity of your condition, which joint is treated, and your activity level. Cortisone does not cure the underlying condition.

Many patients notice improvement within 24-48 hours, with maximum benefit at about one week. Some experience a temporary flare of pain for 1-2 days after the injection before relief begins. This is normal and resolves quickly.

Most doctors recommend no more than 3-4 cortisone injections per joint per year. Frequent injections can weaken cartilage, tendons, and ligaments over time. Your doctor will help determine the appropriate schedule for your situation.

Repeated cortisone injections can damage cartilage, weaken tendons, and cause bone loss near the injection site. Limiting frequency protects your joint health. If you need more frequent relief, your doctor may suggest alternative treatments.

Common side effects include temporary pain flare, facial flushing, and mild skin lightening at the injection site. Less common effects include infection, tendon weakening, and temporary blood sugar spikes in diabetics. Serious complications are rare.

Research suggests that frequent cortisone injections may accelerate cartilage breakdown over time. However, occasional use for acute flares is generally considered safe. Discuss the risks and benefits with your doctor for your specific situation.

You will feel a brief pinch when the needle enters and possible pressure during injection. Most patients tolerate it well. Your doctor may numb the area first with a cold spray or local anesthetic. The procedure takes only a few minutes.

Yes, most patients can drive themselves home. Your joint may be temporarily numb or stiff, so some people prefer to have someone else drive. You can resume normal activities but should avoid strenuous exercise for 24-48 hours.

Rest the treated joint for 24-48 hours and avoid strenuous activities. Apply ice if you experience soreness. Watch for signs of infection like increasing pain, redness, swelling, or fever. Contact your doctor if these occur.

Cortisone reduces inflammation for quick relief lasting weeks. Gel injections (hyaluronic acid) lubricate the joint for longer-lasting relief (6-12 months). Cortisone is better for acute flares; gel injections are better for ongoing management.

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Yes, some doctors combine both in a single treatment. Cortisone provides immediate relief while gel injections provide longer-term benefits. This combination approach is sometimes called a hybrid injection and can be effective for moderate arthritis.

Yes, Medicare Part B covers cortisone injections when medically necessary. You pay 20% coinsurance after meeting your annual deductible. The cost is typically $20-$60 per injection after Medicare pays its share.

Yes, cortisone can be injected into virtually any joint including knees, hips, shoulders, wrists, ankles, and small joints of the hands and feet. It is also used for bursitis, tendinitis, and other soft tissue inflammation.

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Cortisone can temporarily raise blood sugar levels for several days after injection. If you have diabetes, inform your doctor and monitor your glucose closely. The benefits often outweigh risks, but your treatment plan may need adjustment.

A single cortisone injection typically does not cause weight gain. However, frequent injections over time can contribute to increased appetite and fluid retention. One or two injections per year are unlikely to affect your weight.

If cortisone no longer provides adequate relief, your doctor may recommend gel injections, physical therapy, regenerative treatments, or surgical options. Declining response often indicates worsening arthritis that may need different management approaches.

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Cortisone is a synthetic version of cortisol, your body's natural stress hormone. Cortisone in injections is more potent and longer-lasting than natural cortisol. Common medications used include triamcinolone, methylprednisolone, and betamethasone.

Cortisone is best for acute inflammation, pain flares, and quick relief. Gel injections are better for ongoing arthritis management and longer-lasting results. Many patients use cortisone for flares and gel injections for maintenance.

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