Quick Answer
Prolotherapy and Cortisone take different approaches to joint pain relief. Prolotherapy works by irritant triggers healing response, while Cortisone works by anti-inflammatory steroid. Prolotherapy typically lasts variable (months), compared to 6-12 weeks for Cortisone.
How They Compare
| Factor | Prolotherapy | Cortisone |
|---|---|---|
| Mechanism | Irritant triggers healing response | Anti-inflammatory steroid |
| Duration | Variable (months) | 6-12 weeks |
| Sessions | 4-6 sessions needed | Single injection |
| Insurance | Not covered | Universally covered |
| Cost | $200-600/session | $100-300 |
Who Is Each Best For?
Consider Prolotherapy if:
- You want variable (months) of relief
- Irritant triggers healing response
- Your doctor recommends this approach
Consider Cortisone if:
- You prefer 6-12 weeks of relief
- Anti-inflammatory steroid
- Insurance coverage is important to you
Cost and Insurance
Prolotherapy typically costs $200-600/session, while Cortisone costs $100-300. Check with your insurance provider for specific coverage details.
Frequently Asked Questions
Is Prolotherapy better than Cortisone?
Neither is universally “better.” Prolotherapy and Cortisone work differently and suit different patients. Your doctor can help determine which fits your situation based on your OA severity, medical history, and treatment goals.
Can I try both?
In many cases, yes. Some patients try one approach first and switch if results are insufficient. Discuss a treatment sequence with your provider.
Which has fewer side effects?
Both are generally well-tolerated. Prolotherapy has specific considerations related to its mechanism, while Cortisone has its own risk profile. Ask your doctor about side effects relevant to your health history.
Does Medicare cover both?
Coverage varies. Check our Medicare coverage guides for detailed information on what’s covered.
How do I decide?
Start with a conversation with your doctor about your specific condition, pain level, and goals. Consider factors like convenience, cost, duration of relief, and your comfort level with each approach.
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