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Treatment Comparison

Supartz vs Euflexxa

Compare Supartz (5 weekly, avian) with Euflexxa (3 weekly, non-avian). Key differences in injection count, allergy safety, and protocols.

Side-by-Side Comparison

Injections Needed

Supartz 5 weekly
Euflexxa 3 weekly

Source Material

Supartz Avian
Euflexxa Bacterial fermentation

Bird Allergy Safe

Supartz No
Euflexxa Yes

Molecular Weight

Supartz Medium (620-1,170 kDa)
Euflexxa Medium (2.4-3.6M Da)

Office Visits

Supartz 5
Euflexxa 3

Self-Pay Cost

Supartz $600-$1,000
Euflexxa $600-$900

Duration

Supartz Up to 6 months
Euflexxa 6+ months

Medicare Coverage

Supartz Yes
Euflexxa Yes

It Depends on Your Situation

Supartz requires 5 injections but may provide extended delivery. Euflexxa needs only 3 injections and is safe for bird allergies.

Best for: Supartz for extended protocol; Euflexxa for allergy safety and fewer visits.

5 Visits vs. 3 Visits

Supartz requires 5 weekly injections. Euflexxa requires only 3. Both are multi-injection treatments—but Euflexxa also offers allergy safety.


Side-by-Side Comparison

FactorSupartzEuflexxa
Injections5 weekly3 weekly
SourceAvianNon-avian
Bird allergy safeNoYes
Self-pay$600-$1,000$600-$900
Office visits53
DurationUp to 6 months6+ months

Key Differences

Supartz Advantages

  • Extended delivery - 5 injections may provide more gradual buildup
  • Established track record - FDA approved since 2001
  • Supartz FX option - 3-injection variant available

Euflexxa Advantages

  • Fewer visits - 3 vs. 5 appointments
  • Bird allergy safe - No animal-derived ingredients
  • Less time commitment - 40% fewer appointments

Making Your Decision

Choose Supartz if:

  • No avian allergies
  • You prefer gradual 5-week delivery
  • Your provider has strong Supartz experience

Choose Euflexxa if:

  • You have bird/egg allergies
  • Fewer appointments is important
  • You prefer non-animal products

The Bottom Line

Euflexxa requires 40% fewer visits and is safe for allergies. Supartz provides extended delivery over 5 weeks. Both are effective—choose based on your schedule and allergy status.

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