Convenience vs. Flexibility
This comparison pits the most convenient option (Synvisc-One: one visit) against the most accessible option (Euflexxa: safe for allergies, often cheaper). Both deliver 6 mL of HA total—just differently.
Side-by-Side Comparison
| Factor | Synvisc-One | Euflexxa |
|---|---|---|
| Injections | 1 | 3 weekly |
| Source | Avian | Non-avian |
| Bird allergy safe | No | Yes |
| Volume | 6 mL (once) | 6 mL (2 mL × 3) |
| Molecular weight | Very high (6M Da) | Medium (2.4-3.6M Da) |
| Self-pay | $800-$1,200 | $600-$900 |
| Office visits | 1 | 3 |
| Duration | Up to 6 months | 6+ months |
Synvisc-One: Maximum Convenience
Advantages
Considerations
Euflexxa: Accessible and Affordable
Advantages
Considerations
The Tradeoff: Time vs. Money
| Factor | Synvisc-One | Euflexxa |
|---|---|---|
| Time investment | 1 visit (30 min) | 3 visits (2+ hours total) |
| Total cost | Higher | Lower |
| Convenience | Maximum | Moderate |
| Allergy-friendly | No | Yes |
Making Your Decision
Choose Synvisc-One if:
- No bird/egg allergies
- Convenience is your priority
- You can’t make multiple appointments
- You want highest molecular weight
Choose Euflexxa if:
- You have avian allergies
- Cost is a primary concern
- You can easily attend 3 weekly visits
- You prefer smaller individual injections
The Bottom Line
Synvisc-One wins on convenience—one visit, one copay, done.
Euflexxa wins on accessibility—allergy-safe, lower cost, smaller injections.
Both deliver 6 mL of HA total and provide similar duration of relief. Your allergy status, schedule, and budget should guide the decision.
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