Rheumatoid Arthritis
An autoimmune disease where the immune system attacks joint linings, causing inflammation and damage. Different from osteoarthritis in cause and treatment.
Extended Definition
Rheumatoid arthritis (RA) is an autoimmune condition where the body’s immune system mistakenly attacks the synovium (joint lining), causing chronic inflammation and progressive joint damage.
RA vs. Osteoarthritis
| Factor | Rheumatoid Arthritis | Osteoarthritis |
|---|---|---|
| Cause | Autoimmune | Wear-and-tear |
| Pattern | Symmetric (both sides) | Asymmetric possible |
| Joints affected | Often hands, wrists first | Weight-bearing joints |
| Morning stiffness | Over 1 hour | Under 30 minutes |
| Inflammation | Systemic | Local |
| Treatment | Immunosuppressants | Pain management, HA injections |
Why It Matters
HA injections are typically used for osteoarthritis, not rheumatoid arthritis. RA requires disease-modifying drugs (DMARDs) to suppress the immune response. If you have RA, your treatment plan will be different—consult a rheumatologist.
Related Terms
More Conditions Terms
View allBilateral Arthritis
Arthritis affecting the same joint on both sides of the body, such as both knees or both hips. Common in osteoarthritis due to similar wear patterns.
Bone Spur
A smooth, bony growth that develops along the edges of bones, especially in joints affected by osteoarthritis. Also called an osteophyte.
Bone-on-Bone
A colloquial term describing advanced osteoarthritis where cartilage has worn away completely, allowing direct contact between bone surfaces. Often painful and may require surgery.
Chondromalacia
Softening and deterioration of cartilage, most commonly affecting the underside of the kneecap. Often considered an early stage of patellofemoral arthritis.
Crepitus
A crackling, popping, or grinding sensation or sound that occurs during joint movement, often felt or heard when bones with damaged cartilage rub together.