Hymovis × Blue Cross Blue Shield

Hymovis Insurance Coverage with Blue Cross Blue Shield

Everything you need to know about getting Hymovis viscosupplementation injections covered under Blue Cross Blue Shield, including requirements, costs, and approval steps.

Not Typically Covered

Blue Cross Blue Shield does not typically cover Hymovis. See alternatives and appeal options below.

Prior Authorization Required

Coverage Details

Coverage Status

Not Covered

Prior Authorization

Required

Estimated Cost

$600-$900 per course (2 injections)

Self-pay (without coverage)

Injection Schedule

2 weekly injections

Can repeat Every 6 months as needed

Coverage Notes: Commercial coverage discontinued Jan 2026. Medicare Advantage may still cover.

Prior Authorization for HA Injections

Blue Cross Blue Shield requires prior authorization before Hymovis injections. Your provider's office typically handles this process. Here's what to expect:

1. Your doctor submits a prior authorization request with clinical documentation
2. Include X-ray evidence and records of failed conservative treatments
3. Approval typically takes 5-15 business days
4. If denied, you have the right to appeal (see below)

Expected Costs

Scenario	Estimated Cost
Self-pay (without insurance)	$600-$900 per course (2 injections)
Number of injections	2 weekly injections
Repeat frequency	Every 6 months as needed

Costs are estimates and may vary based on your specific plan, location, and provider. Contact Blue Cross Blue Shield to verify your exact out-of-pocket costs.

How to Get Approved

If your Hymovis treatment has been denied by Blue Cross Blue Shield, here are steps to appeal:

1 Request specific denial reason in writing
2 Document all conservative treatments tried
3 Ask about Medicare Advantage enrollment if 65+
4 Request external review through state insurance department
5 Check for state-mandated coverage requirements

Common Denial Reasons

Commercial plan exclusion effective January 2026
Step therapy requirements not completed
Non-preferred brand used without exception
Prior authorization not obtained
Medical necessity documentation insufficient

Other HA Brands & Blue Cross Blue Shield

Compare how Blue Cross Blue Shield covers other viscosupplementation brands:

Brand	Schedule	Source	Cost w/ Insurance	Details
Synvisc-One	Single injection	Avian	$100-$300 with Medicare/insurance	View
Monovisc	Single injection	Avian	$100-$350 with insurance	View
Durolane	Single injection	Non-Avian	$150-$400 with insurance	View
Gel-One	Single injection	Avian	$100-$300 with insurance	View
Euflexxa	3 weekly injections	Non-Avian	$75-$250 with insurance	View
Gelsyn-3	3 weekly injections	Non-Avian	$75-$200 with insurance	View
SynoJoynt	3 weekly injections	Non-Avian	$75-$200 with insurance	View
Orthovisc	3-4 weekly injections	Avian	$100-$250 with insurance	View

Compare Insurance Plans for Hymovis

See how other insurance plans cover Hymovis:

What Your Doctor Needs to Submit

To get Hymovis approved by Blue Cross Blue Shield, your doctor's office will need to prepare the following documentation:

Knee Osteoarthritis Diagnosis

Confirmed diagnosis of knee OA using ICD-10 code M17 (or appropriate subcode). The documentation should include clinical findings from physical examination.

X-Ray Evidence

Radiographic imaging showing joint space narrowing, osteophytes, or other degenerative changes consistent with knee osteoarthritis. Images should be recent (within 6-12 months).

Failed Conservative Treatment

Records showing the patient tried and failed conservative treatments for at least 3-6 months. This includes physical therapy, exercise, weight management, OTC pain medications, and/or prescription anti-inflammatories.

Letter of Medical Necessity

A written statement from the treating physician explaining why Hymovis is medically necessary for this patient, including why conservative treatments were insufficient.

Prior Authorization Form

Complete the Blue Cross Blue Shield prior authorization form with all required fields. Include the J-code for Hymovis, units needed, and treatment location. Submit well in advance of the planned injection date.

Tip: Ask your doctor's office to confirm they have all required documentation before submitting to Blue Cross Blue Shield. Incomplete submissions are the most common reason for delays and initial denials.

Frequently Asked Questions

Does Blue Cross Blue Shield cover Hymovis?

Hymovis is not typically covered by Blue Cross Blue Shield. The self-pay cost ranges from $600-$900 per course (2 injections). You may want to appeal the denial with supporting documentation from your doctor, or consider alternative brands that may be covered.

How much does Hymovis cost with Blue Cross Blue Shield?

Since Blue Cross Blue Shield does not typically cover Hymovis, you would pay the full self-pay cost of $600-$900 per course (2 injections) for the 2 weekly injections injection schedule. You can repeat treatment Every 6 months as needed. Ask your doctor about covered alternatives or consider filing an appeal.

Do I need prior authorization for Hymovis with Blue Cross Blue Shield?

Yes, Blue Cross Blue Shield requires prior authorization before Hymovis injections. Your doctor's office will submit clinical documentation including your diagnosis, X-ray results, and records of failed conservative treatments. The process typically takes 5-15 business days. Plan ahead so approval is in place before your scheduled injection date.

What is the injection schedule for Hymovis?

Hymovis uses a 2 weekly injections schedule. It is manufactured by Fidia Pharma USA and uses a non-avian (biofermented) hyaluronic acid source with Medium-High molecular weight. Treatment can be repeated Every 6 months as needed.

What if Blue Cross Blue Shield denies coverage for Hymovis?

If denied, you have the right to appeal. Ask for the denial reason in writing, then work with your doctor to submit an appeal including X-ray evidence of osteoarthritis, documentation of at least 3-6 months of failed conservative treatments (physical therapy, OTC pain relievers, exercise), and a letter of medical necessity from your doctor. Many initially denied claims are approved on appeal. You can also ask about alternative covered brands.