The Key Question: Any Bird Allergies?
Monovisc and Durolane are both excellent single-injection HA treatments—but your allergy status determines which is right for you.
- No bird allergies? Either works. Monovisc is typically cheaper.
- Bird/egg allergies? Durolane is your only single-injection option.
Side-by-Side Comparison
| Factor | Monovisc | Durolane |
|---|---|---|
| Source | Avian (rooster comb) | Non-animal (NASHA) |
| Bird allergy safe | No | Yes |
| Manufacturer | DePuy Synthes (J&J) | Bioventus |
| Volume | 4 mL | 3 mL |
| Self-pay | $700-$1,100 | $900-$1,300 |
| With insurance | $100-$350 | $150-$400 |
| Injections needed | 1 | 1 |
| Duration | Up to 6 months | Up to 6 months |
Monovisc: The Affordable Single-Shot
Advantages
Limitations
Durolane: The Allergy-Safe Option
Advantages
Limitations
Allergy Decision Tree
Do you have allergies to birds, eggs, feathers, or poultry?
→ Yes: Choose Durolane (only safe single-injection option)
→ No: Either works. Consider Monovisc for lower cost.
→ Not sure: Get tested before treatment, or choose Durolane to be safe.
Making Your Decision
Choose Monovisc if:
- You have no bird/egg allergies
- Cost is a significant factor
- Your insurance prefers J&J products
Choose Durolane if:
- You have or might have avian allergies
- You prefer non-animal products
- Smaller injection volume matters to you
The Bottom Line
Allergies Determine the Choice
For most patients without avian allergies, Monovisc offers comparable effectiveness at lower cost.
For patients with allergies to birds or eggs, Durolane is the only single-injection option—and the premium is worth avoiding an allergic reaction.
Find Single-Injection Providers
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- 1 We'll verify your insurance coverage
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- 3 Contact you to discuss your options
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